Collection Occupational hygiene, Issue 32, 2001 year

Comparative study of cadmium toxic influence on neutrophils and lymphocytes of rat peripheral blood in experiments in vivo and in vitro

VA.Stezhka, N.N.Dmytrukha, T.N.Pokrovskaja, T.A.Bilko, E.G.lMinpeka

doi

Institute of Occupational Health of the Academy of Medical Sciences of Ukraine, Kiev

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There are in paper results of comparative study of cadmium toxic effects on neutrophils and lymphocytes of rat peripheral blood in experiments in vivo and in vitro. It was proved that cation Cd2* has immunotoxic effect properties. Universal mechanism of realization of immu- notoxic effect of heavy metals compound on immunocompetent cells which depends on modification of specialized properties of citoplasmatic membranes was discovered.

Key words: cadmium, immunotoxic effect

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